Section: Partnerships and Cooperations

International Research Visitors

Prof. Dima Kozakov visited the group in 2014. Dima Kozakoz is a Research Assistant Professor at Boston University (http://www.bu.edu/bmerc/people/affiliated-faculty/ ). Proteomics revolution provided blue-print of molecular interactions in the cell, however, full mechanistic understanding of how molecules interact comes only from three-dimensional structures. As was shown by Protein Structure Initiative (PSI), it is much more difficult to obtain structures of the protein complexes using high resolution experimental approaches, such as an X-ray or NMR, rather than structures of its individual components. Our groups (at Boston University and Inria / LJK Grenoble) have developed highly efficient protein docking approaches, which were successful in the CAPRI protein docking competition, and thus our next goal is to apply these to genome scale studies. We hope that structural modeling can not only provide potential complex structures, but also clean up uncertainty of the data obtained from high-trhoughtput approaches.